The Neotree project is a transformative technology initiative developed through a partnership between leading academic institutions, local clinicians, and digital specialists. This innovative system uniquely combines data collection, clinical decision support, and education to enhance newborn care in low-resource settings. The Neotree system, backed by seven years of rigorous research from University College London and recognized with the Wellcome Trust Innovator Award, empowers healthcare professionals to improve care quality, strengthen health systems, and significantly reduce newborn mortality. Operating in Zimbabwe and Malawi, Neotree has the potential to save over half a million babies each year. It aims to revolutionize newborn care in low-resource hospitals by providing healthcare professionals with a comprehensive technology system that supports data-driven decisions and educational growth, with the ultimate goal of substantially decreasing newborn mortality rates. The project has transitioned to a routine operational stage, focusing on maternal and child health through software-based decision support. Neotree's implementation and outcomes have been significant, benefiting over 10,000 individuals. Key publications documenting its development and impact include studies on the NeoTree application, its usability in low-resource neonatal units, and its role in improving infection management in neonatal units in Malawi and Zimbabwe. Funded by University College London and the Wellcome Trust, the Neotree project represents a significant advancement in neonatal healthcare, demonstrating the potential for technology to transform health outcomes in resource-limited settings. For further details, relevant research can be accessed through various academic publications and project reports.